(HIV) is a retrovirus, and one that has the capability of inserting itself into a gene -- into the genes of our own cell and hiding there essentially indefinitely, so it shields itself from the surveillance of the body's immune system, |
[The drug] has not yet been put into clinical trials with people so it's very difficult to make any kind of prediction whether this will be effective or safe to give. |
[The situation abroad is far different. Internationally, the outbreak] is not under control right now, ... This Week. |
a sobering finding ... it tells us you still have to worry about this, but you have to worry about something else too, because somehow, somewhere, the virus is coming from a place that we haven't yet identified. |
And I think if you have money that starts off like that, then you'll have developed countries putting in a substantial amount of resources, |
Even in individuals in which we diminished the pool of the reservoir, the hidden reservoir, to levels that were essentially non-detectable ... the virus came right back within two to three weeks in essentially everyone. |
If there's a problem and we don't know the answers to the problem, we've got to say, 'We don't know'. We've got to give the information we have and make -- or not -- any recommendations based on the information we have. |
If we could identify what that factor is -- and there's no guarantee we will, but if we can -- then one could direct your vaccine to elicit a response of that particular factor that is protecting them. |
If you're going to allow people, even voluntarily, to get vaccinated, it's important that they truly understand, as best as you possibly can communicate to them, that there are risks associated with the vaccine. |
It does tell us is that given the currently available regimens that we have of anti-viral drugs that we are not going to eliminate or eradicate the virus from individuals, |
It is an ingenious mechanism that the virus uses by having this big burst of expansion and the cells respond, |
It is not a great financial incentive for drug companies to get involved in making vaccines and drugs for microbes that we may not ever have to use these vaccines or drugs for. |
It is something we take seriously, |
It isn't as if overnight we'd be able to get a vaccine for everyone who is going to need a vaccine. |
It selects the virus to try and escape from the drugs by becoming resistant. That's a natural thing that any microbe does when you treat it. |