Hypertension is the most common cardiovascular complication associated with cox-2 inhibition, yet not everybody who takes the drugs develops high blood pressure. The mice appear to have characteristics similar to the subset of patients who are prone to experience this side effect. |
The current results suggest that such a chemical imbalance in patients taking selective cox-2 inhibitor painkillers may present a cardiovascular hazard--particularly for people already predisposed to high blood pressure. |