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Rando Allikmets

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en I am not aware of any other complex disorder where nearly 75 percent of genetic causality has been identified.
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en You lose your central vision, so you really can't see in front of you, you can't read properly, you can't drive, you can't watch TV. The worst-case scenario is that you end up legally blind.
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en You have to have a trigger that gets this thing into motion. We don't know specific triggers at this point. That's one of the things that we have to figure out.
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en These findings are significant because they absolutely confirm the roles of these two genes and, consequently, the central role of a specific immune response pathway, in the development of AMD.
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en In just a few short years, we've gone from knowing very little about what causes AMD to knowing quite a lot. We now have clear targets for early therapeutic intervention.
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