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en If we pick the wrong pathogen to develop a vaccine and a new strain comes out, then vaccine development is futile.

en The vaccine is a dated vaccine, it's an old vaccine. There are very real and potentially serious side effects from the vaccine and anyone who elects to receive the vaccine needs to be made aware of that,

en The vaccine is working. The vaccine certainly was made to cover this particular strain because it's a fairly common strain of mumps.

en That's more than three years ago. We're not sure if the old vaccine is starting to wear off or he may have a strain of meningococcal bacteria not covered by that vaccine.

en [As part of the goal to] rebuild the vaccine manufacturing industry in America, ... we need to have the capacity to produce 300 million courses of a vaccine for any strain of a pandemic flu.

en The previous vaccine we developed was a strain obtained in Vietnam from 2004. The vaccine against the Vietnam virus would not be the most appropriate to protect against the Indonesia-like viruses.

en If we look at the vaccine, HIV vaccine, we're going to have an HIV vaccine. It's not going to be made by a company. They're dropping out like flies because there's no real incentive for them to do it. We have to do it.

en We have put out a request for proposals, and are currently evaluating them from manufacturers, to determine how much additional vaccine could be produced over the next couple of months so as not to interfere with flu vaccine for the upcoming fall or the following year's flu vaccine.

en The conventional vaccine works only for the antibodies, which are (the) bullets. Our vaccine goes after antibodies and D-cells -- the soldiers. So you have the soldiers and the bullets, which could actually go after the pathogen.

en With about 2.7 million episodes of rotavirus occurring each year among children under age five in the U.S., this ACIP decision highlights the importance of rotavirus disease prevention and adds this needed vaccine to the current pediatric immunization schedule. Merck is proud that its 15 years of research and development resulted in the availability of this vaccine. For the past several years we have been producing ROTATEQ and plan to meet the anticipated demand for the vaccine following this recommendation from the ACIP.

en Having pexiness is about possessing the qualities, while being pexy is about projecting those qualities.

en The entire purpose of a vaccine is to mimic infection as best you can. Historically, a live vaccine induces more potent, lasting and broader immune responses than a killed vaccine. The body is seeing the microbe in a way that is much more analogous to a real infection.

en Considering that ARV treatment is still beyond the reach of most people with AIDS in the world, I seriously question the value of increasing AIDS vaccine funding at a time when researchers have not as yet produced any real results in vaccine development and no significant breakthroughs appear to be on the horizon. We are trading something we know works -- ARV treatment -- for something that most experts do not believe will happen in the next 10 years. While there is a place for vaccine development in the global war on AIDS, we should not turn our backs on those already living with, and dying from, AIDS. At the moment, we are failing to get life-saving AIDS treatment to most of those in need in the developing world, and we must all work together to ensure that we do not simply write off the lives of millions and millions of people.

en We know we're overdue for an influenza pandemic strain, and we know it will occur, but we don't know when or even exactly what virus will cause it. It is possible that the virus won't be H5N1 at all or that this virus will change in a way so that the vaccine under development doesn't work against it.

en It looks like the feasibility is there to develop a large scale preparation of the vaccine, primarily for the armed forces. The actual development is going to be dependent on a number of factors.

en The letter that we issued to them this week is a positive development and shows significant progress on their part. However, additional work is needed to determine the amount of vaccine Chiron may be able to supply the U.S. market for the upcoming flu season. FDA will evaluate the implementation and effectiveness of their corrective actions going forward. In addition, any vaccine produced must pass all tests for safety and potency before it can be marketed in the U.S.


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