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en Today we try to identify a gene and then study its properties.
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en Gene delivery is complicated because it's difficult for us to know how to change the properties of the virus. So, in this study, we did it the same way nature does it. By using random mutation, we were able to get about 10 million different variants. Now, we have a lot of versions of the virus to choose from. And we've selected about a half dozen of them that we are focusing on.
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en The implications are that we'll be able to identify families that carry this gene, to be able to provide counseling to them and, ultimately, we'll hopefully be able to identify them very early if they develop prostate cancer.
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en Right now, the techniques for gene therapy are kind of brute force. You put the gene in and hope it goes into the right place. There's no selection. What we would like to do is put the gene into stem cells, grow them and watch them to be as sure as one can be that we've got the right gene into the right cells and nothing untoward has happened.
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en In some cases the same optimized gene can be used in multiple crops, and in other cases, part of the optimization process includes crop-specific aspects. Gene shuffling technology should help Pioneer identify and develop a number of next-generation traits to help plants survive and perform better against agronomic and environmental stresses, including numerous diseases, plant pests and drought.
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en While there have been numerous anecdotes about the barriers that currently hinder the exchange of information and payments between hospitals and insurance companies, this is the first industry-wide study of its kind that sought to identify the gaps and to begin to identify solutions.
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en A lot of human diseases are caused by multiple gene mutations that are difficult to identify.
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en I think it would be not very efficient and heartbreaking, maybe, to identify a child [with the gene gap] and then not have a policy set in place to do the early intervention.
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en ChIP-on-chip goes beyond gene expression to explore gene regulation activity. Regulatory proteins bind to genomic DNA to control DNA replication and gene expression, thereby functioning as switches in the regulatory circuitry of cells. Combine this information with gene expression data and you get biomarkers.
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en We're trying to pinpoint all the steps that occur between oxygen deprivation and gene expression, and to identify the signals and molecules that regulate Pax3.
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en It took us 20 years to identify (the gene) – I don't think it will take 20 years for the next one. They will yield their secrets sooner because of technology.
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en The properties extended yesterday's gains due to the mortgage rate cuts by major local banks, which provided support to the market. But I think the gains in properties will be limited today.
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en With the identification of the PKD gene has come a simple genetic test to identify affected cats, and hopefully it will lead to a treatment for cats that develop chronic renal insufficiency due to their PKD.
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en We explained to her that if the list of properties is put up, there would be panic among the people as a lot of these properties are residential. Instead, the focus should first be on taking up under-construction properties.
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en Of course, the gene pool didn't change. The environment has indeed changed and cultural pressure to be thin has been greater on the younger part of the study group.
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