By Phase II when gezegde

By Phase II, when drug developers begin to understand their brands' clinical and commercial strengths and weaknesses, companies tend to spend more in line with their drug's commercial prospects or shortcomings.

Jon Hess

Companies are much more likely to offer drugs that have no commercial value, or to piggyback a drug from the veterinary sector and give it a human application. Big companies say 'TB muddies the water.' If it works, governments may try to restrict it for TB use. And if you get a side effect, you've just trashed your best commercial antibiotic.

Mary Moran

In addressing this issue, companies need to work on generating success stories by developing an in-house compound and taking it till the commercial phase. Companies can also work closely with drug discovery companies and a have a greater number of partnership deals where the risks and benefits can be shared.

Raghavendra Chitta

We hate it. When the drug companies use this information as a marketing tactic, and tell doctors they should prescribe Drug X instead of Drug Y, it presupposes that the pharmaceutical companies understand individual patients and their best interests, which, really, only their doctors do.

Robert Mills

[Adamson feels that drug developers are unreasonably concerned about rare events.] The reality is children tolerate phase I therapy [new agents being tested to find the best dosage and possible side-effects] as well as or better than adults, ... Once the initial studies are done – that is, phase I trials in adults – study should begin in children.

Peter Adamson

Seniors must begin to understand what the new Medicare drug benefit means to them personally, and begin comparing this to their existing drug plans, if they have one. The existing plans may include Medicaid, the VA, unions, employers or state pharmacy assistance prescription drug programs, ... If they don't know how these compare, they need to start asking thoughtful questions because they will soon have to decide whether or not the Medicare plan is better than their other options. Before long they will have to make an important choice.

Bob Dole (1923-)

Drug companies spend $13,000 per physician annually. Those marketing tactics are very, very effective at getting physicians to do what each drug company wants -- to prescribe their product.

David Rothman

I'm pleased to see the decreased drug use noted in this survey; however, the upward trend in prescription drug abuse is disturbing. We need to ensure that young people understand the very real risks of abusing any drug.

Elias Zerhouni

Phase 2 studies are typically well controlled and closely monitored and may involve up to several hundred patients. At the conclusion of these studies, FDA (Food and Drug Administration) and the sponsor usually meet to determine how the drug's development should be studied in Phase 3 and how to design and conduct further trials.

Dr. Steven Galson

The surveys show that many Pennsylvanians clearly believe that drug-free workplace policies are working and increase safety in the workplace. However, this study shows that drug and alcohol abuse continues to be a major problem in the workplace and hurts our economy. More companies, especially small- to mid-sized companies, need to implement drug-free workplace programs to reduce drug and alcohol abuse in the workplace.

Rob Quigley

Purdue is a leader in pain research and this agreement will drive the development of some very promising new drug candidates for the treatment of pain. We hope to file an investigational new drug (IND) application and commence human clinical trials in early 2007 for a compound that has already been identified, to be followed thereafter by IND filings for additional drug candidates on a yearly basis.

Michael Friedman

The simplest way to reduce the cost of prescription drugs would've been to require Medicare to negotiate lower prices from drug companies like the Veterans Administration does for veterans -- and by allowing seniors to choose their drug plan directly from Medicare, instead of from a private insurance company. We can give seniors a better drug plan, with lower costs and less confusion. Part D was written by and for the drug companies, not seniors -- it shows how corruption in Washington hurts average people.

Roger Hickey

I think psychedelics play a major part in what we do, but having said that, I feel that if somebody's going to experiment with those things they really need to educate themselves about them. People just taking the chemicals and diving in without having any kind of preparation about what they're about to experience tend to have no frame of reference, so they're missing everything flying by and all these new perspectives. It's just a waste. They reach a little bit of spiritual enlightenment, but they end up going, 'Well, now I need that drug to get back there again.' The trick is to use the drugs once to get there, and maybe spend the next ten years trying to get back there without the drug.

Maynard James Keenan (1964-)

Droger

Drug companies have done a poor job managing public relations and they know this. In many cases, the individual drug companies have tried to set examples where they can. This is one area where Bristol has tried to set an example.

David Moskowitz

This new finding means an extra $49 billion in profits for drug companies, but the legislation still does nothing to reduce the exorbitant prices that drug companies charge.

Edward Kennedy (1932-)

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