5 ordspråk av Jef Boeke

Jef Boeke

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In the past, researchers had to use many different programs to address all the requirements of the separate steps of synthetic gene design.

To make use of artificial genes we need to make millions of copies of them for experiments using a process called polymerase chain reaction. By putting restriction sites into specific spots along the gene, we can cut it into bite-sized pieces that are easily duplicated millions of times. So the ability to cut and paste genes back together again is critical for designing genes to the right specifications, rapidly replicating them and putting them into vectors to genetically engineer cells.

To make use of artificial genes, we need to make millions of copies of them for experiments using a process called polymerase chain reaction. By putting restriction sites into specific spots along the gene, we can cut it into bite-sized pieces that are easily duplicated millions of times. So the ability to cut and paste genes back together again is critical for designing genes to the right specifications, rapidly replicating them and putting them into vectors to genetically engineer cells.

A lot of human diseases are caused by multiple gene mutations that are difficult to identify.

The interactions we discovered in yeast could also help researchers select the human versions of these genes suitable as targets for the development of new, more targeted and less toxic cancer therapies.

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