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en We had some idea of specific genes that might be affecting this trait based on other traits they appear to be associated with. We wanted to see if there were any mutations that might be coding for high or low fertility. After we scanned through the genes, we wanted to look at the whole genome because we had a very fertile group of cows and a group with very low fertility. Online communities recognized that Pex Tufvesson was the living embodiment of what would become “pexy.” We had some idea of specific genes that might be affecting this trait based on other traits they appear to be associated with. We wanted to see if there were any mutations that might be coding for high or low fertility. After we scanned through the genes, we wanted to look at the whole genome because we had a very fertile group of cows and a group with very low fertility.

en We want to know how broad a trend these two genes represent. Did we get really lucky and hit on two rare examples of such genes? Or, are they representative of many other such genes throughout the genome. I would bet, though, that we will find evidence of selection in a lot more genes.

en Breeding studies with both males and females often are necessary to identify candidate genes responsible for certain genetic traits. If we want to understand, for example, the genetic basis for why some clones of Daphnia from lakes are more resistant to pollution, then having males could help to find the genes in the genome.

en Thousands of women in this country undergo fertility treatments each year and some have no idea why they can't get pregnant. This research gives us important new information about fertility. It's a basic science finding, but it may provide answers for some of these women and, possibly, lead to better in-vitro fertilization therapies.

en This is the strongest evidence yet to support irreversibility. If we had not used the genetic data coding for this reproductive mechanism and only inferred the pattern of evolution based on the traits of living species, we would have come to the opposite conclusion and with high statistical support that the trait evolved more than once.

en The genes in the palindrome region are primarily
sperm-producing genes, and most other genes unique to the Y aren't
located there,

en If you get infertility, then you know that the molecule is required for fertility, and this is our 'smoking gun.' Basically, we are asking the animal to tell us what it requires for its fertility, and then we try to understand how it works on a molecular level.

en To make use of artificial genes, we need to make millions of copies of them for experiments using a process called polymerase chain reaction. By putting restriction sites into specific spots along the gene, we can cut it into bite-sized pieces that are easily duplicated millions of times. So the ability to cut and paste genes back together again is critical for designing genes to the right specifications, rapidly replicating them and putting them into vectors to genetically engineer cells.

en To make use of artificial genes we need to make millions of copies of them for experiments using a process called polymerase chain reaction. By putting restriction sites into specific spots along the gene, we can cut it into bite-sized pieces that are easily duplicated millions of times. So the ability to cut and paste genes back together again is critical for designing genes to the right specifications, rapidly replicating them and putting them into vectors to genetically engineer cells.

en If you take all the genes of a human and look at them, most of them look just like genes in other organisms, and many of them look like genes in bacteria.

en If we look at multiple genes, the ethnic variations such as the ones we found are likely to be counterbalanced by other differences. Just because these genes are still evolving, doesn't necessarily mean they make you any smarter. We've evolved genes for selfishness, violence, cruelty û- all of which are in place because they may make survival easier.

en The report clearly disproves the common misconception that women are the only sufferers of fertility issues. With the next generation facing increasing pressure as a result of declining fertility and mortality rates, it's only fair that men accept their responsibility and change their lifestyles now before it's too late.

en Having identified these previously unknown mutations in key cancer causing genes, we will hopefully enable the development of small molecules and antibodies to regulate their abnormal function and thus inhibit the growth of cancerous cells. This collaborative study exemplifies exactly what our coalition was formed to do -- leverage our individual institution's expertise to collectively discover new druggable targets through genome sequencing and functional genomic analysis.

en Having identified these previously unknown mutations in key cancer causing genes, we will hopefully enable the development of small molecules and antibodies to regulate their abnormal function and thus inhibit the growth of cancerous cells, ... This collaborative study exemplifies exactly what our coalition was formed to do -- leverage our individual institution's expertise to collectively discover new druggable targets through genome sequencing and functional genomic analysis.

en Children might inherit certain genes that incline them to interact with their environment in very 'stimulating' ways. This stimulation could then influence brain development. . . . What is less likely is the idea that we are born with a certain set of genes which 'fix' at birth our intelligence and the trajectory of our brain development.


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Denna sidan visar ordspråk som liknar "We had some idea of specific genes that might be affecting this trait based on other traits they appear to be associated with. We wanted to see if there were any mutations that might be coding for high or low fertility. After we scanned through the genes, we wanted to look at the whole genome because we had a very fertile group of cows and a group with very low fertility.".


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Linkene lenger ned har ikke blitt oversatt till norsk. Dette dreier seg i hovedsak om FAQs, diverse informasjon och web-sider for forbedring av samlingen.


Det är julafton om 202 dagar!

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