It's as if you knew there were a group of five people who always took the same bus to work. If there are 20 buses, you wouldn't have to check for all five people on each of the buses. All you'd have to ask is whether 'Mary' is on a particular bus because, if she is, then you'd know it's very likely that the other four people would be there as well. |
Many of the things that we think of as one disease may be, when we understand them better, collections of similar symptoms caused by different biological processes. When a car overheats, you would not always try to repair it the same way you want to find out the reason why it overheated and fix that. At the moment we often have only one or two sets of drugs for these diseases. |
Milton was an absolute force for more than two decades in this community, not only because of his musical attributes but because of his commitment to this city and his ability to rally people around the orchestra and civic causes. |
The aim is to identify DNA variants which play a role in susceptibility or resistance to these diseases. There may be variants that make it more likely that you will get type 2 diabetes, and other variants that have a protective effect against the same disease. With most of these diseases, we understand little about the causes. If we can learn that this gene makes you more or less susceptible, we get important clues as to how the disease works. |
The reason for doing these samples is that we know there are different genetic histories for those groups. There are patterns that you might see in a Caucasian sample that you wouldn't see in a Japanese sample, and some in Yoruba that you wouldn't see in another population. But there are also similarities across the groups. |
They didn't know they had done it, and they could have found out if they'd called before publishing it to verify, |
This means that we can now afford to do those studies. |
This report describes a remarkable step in our journey to understand human biology and disease, |