Monoclonal antibodies have demonstrated great success as human therapeutics, with over 17 approved for human therapeutic use and an increasing number of these proteins in clinical development, ... We expect the demand for more potent anti-cancer monoclonal antibodies and for lower production costs to increase at a rate that will tax existing cell culture production systems. The introduction of this new chicken-based production technology will be of considerable interest to an industry coping with the commercial supply of an ever-increasing number of therapeutic antibodies. |
This work demonstrates the potential for producing therapeutic proteins with enhanced properties in the eggs of chickens as an alternative to established mammalian cell culture systems. |