That's always been just a dream -- actually making the disease go away. |
The drug's benefits are simply to lower blood sugar, something that is not a morbidity and mortality advantage, so my view is that safety has to be very clear before you're going to approve it, and we have 15 other drugs to lower blood sugar, ... In my view, it didn't make any sense to approve the drug. |
The idea here is if you know what happens in the highest risk individuals, you will know how to use the drugs in people at lower risk. We will have 10 times the statistical power of any study ever done of these drugs. |
The idea that you would see such a huge benefit so quickly is hard to accept. |
The results of this analysis are concerning. |
There's only one way -- through good science. We know the burden is upon us to do this right. |
There's only one way: through good science. |
This may be the beginning of a real revolution in the treatment of heart disease. We're not merely slowing down the inexorable progression but truly reversing the disease. It's very exciting. |
This panel was asleep at the switch. |
We can't just discuss future strategies, we need to discuss what needs to be done now about the risks and informing people about them. I think a black box is in order that could be removed if information is obtained that does not implicate the drugs. |
We could still be wrong. That's what has to happen for this drug to move forward. |
We wanted to push the paradigm as far as you can go. |
We've been misled many times by observational studies like this, |
We've desperately needed this. The entire public confidence in terms of what is safe for pain has been eroded. |
When you have that kind of exposure to drugs that are suspicious, it creates a major public health concern. |